DNA and RNA get broken down into mononucleotides by the nucleases (DNase and RNase).pong
“Congratulations Mr. and Mrs. Smith. You have a healthy baby with all his fingers and toes, and a prehensile tail.”
DNA and RNA get broken down into mononucleotides by the nucleases (DNase and RNase).Well wouldn’t we be absorbing micro-DNA from non GM food too? In fact genetically engineered crops could be designed to make the foods safer.
So if I eat the brains and liver of a person, say someone I beat in a fight, I get that person’s smarts and strength? Same concept but with rice.
i ma not a wuss.
Reminds me of the study of flat worms and electric shocks.
Platyhelminthese (its been 50 years not sure of the spelling:) were subjected to light and then an electric shock. After a period of time the worms braced for a shock whenever the light came on. The worms were then ground up and fed to other flat worms which had not been subjected to the light/shock routine. When the light came on, they braced for a shock. Cool huh:) Remember that next time you eat flat worms.
We are screwing with the primordial forces of nature with all the arrogance of a god (small g). We do not know what we do not know. No good will come of this.
The last to paragraphs of this tripe from its vitamin commercial filled website:
“But where is the FDA in all this? Aren’t they watching out for our safety with respect to GMO foods? Well, in a word: no. They aren’t working for you or any of the other 99% of Americans. The FDA is working for … Monsanto itself along with a collection of the other most wealthy corporations in the world. This is why I gave one of my recent blogs the title: Occupy FDA: Smart Publications Alternative Heath Solutions Threatened. I make the modest proposal that the FDA should be working for us – the 99% – or it should be immediately de-funded.
If more studies like this one come to light, it’s likely that perception about GMO food safety will also change. In the meantime, as we begin to understand just how complex the relationship between food and our health really is, keeping GMO foods out of our kitchens and gardens is more important than ever.”
How about this keep the government out of it all together. I am an adult and I can pick my own foods with out anyone’s help. Since we do not have anything in our food chain that is not genetically modified I am not concerned.
By the way have you read about how viruses invade our DNA?
So, when I eat rice I pick up its DNA?? Wow, my cells are rice cells! Who knew?!
We should single out really strong and smart people and eat them! Think about it. One person was strong and smart but 100 people could be once they eat them.
People againt GMF are Luddites.
“First discovered only a decade ago, microRNA is a short, single-stranded RNA molecule that plays a pivotal role in how genes express themselves.”
This is critical, and part of how far we have come in understanding how incomplete early (and some still) understandings of HOW AND WHY a gene (a code that provides instruction to produce a certain protein) does, or doesn’t actually EXPRESS the instruction it is capable of.
There are other insights that demonstrate that “influences” from the environment a gene is in have a role in determining its “expression” (will it or will it not direct the production of the protein it would “normally” provide the instruction for).
RNA and microRNA are only some of the influences that can cause a gene that is present to be active or not.
The “genes” alone are not running the show. Imagine that!!???
This is confirmation of what we have been learning in so many areas of science in the last century. We reach a great new understanding or insight and as we explore it we find it opened a window showing us that we have gained more questions in this area than we even knew to ask before.
Since it happens with food whether GMO or not who cares. Just stupid luddite panic.
I ate so much rice growing up in Louisiana I should be the RiceGirl superhero by now if this had any relation to reality.
Apparently not a new process as humans have been eating pretty much everything they can keep down for a very long time.
This is from the study. Note this comment: “Food-derived miRNAs may serve as a novel essential nutrient”
Original Article
Cell Research (2012) 22:107–126. doi:10.1038/cr.2011.158; published online 20 September 2011
Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA
Food-derived miRNAs may serve as a novel essential nutrient
It has been widely reported that downregulation of LDLRAP1 increases plasma LDL level35,36. In the present study, direct reduction of LDLRAP1 in mouse liver by RNAi significantly elevated plasma LDL level (Supplementary information, Figure S6A-S6C), confirming that LDLRAP1 is a gene candidate responsible for plasma LDL removal. Interestingly, an elevated level of MIR168a but a decreased LDLRAP1 in mouse liver were detected after just 6 h of rice feeding (Figures 2C and 5B), indicating that exogenous plant MIR168a from food intake can quickly change mouse liver LDLRAP1 level. Continuous downregulation of mouse liver LDLRAP1 level by MIR168a through rice feeding (Figure 6E and 6F) resulted in an elevation of the plasma LDL-cholesterol level after 3 days (Figure 6G), implicating a physiological relevance of food-derived plant MIR168a. Rice feeding-induced reduction of LDLRAP1 protein and elevation of plasma LDL-cholesterol level could be largely reversed by anti-MIR168a ASO (Figure 6I-6K), confirming that the rice feeding-mediated physiological alteration is specifically due to the targeting of mouse liver LDLRAP1 by MIR168a.
This conclusion is also supported by the observation that chow diet with addition of mature MIR168a significantly enhanced the levels of mouse liver MIR168a (Figure 6N) and plasma LDL-cholesterol (Figure 6Q) but decreased mouse liver LDLRAP1 protein level (Figure 6O and 6P). Interestingly, food intake, possibly via intestinal epithelia of GI track, may represent a general pathway for uptake of food-derived or food-associated miRNAs. As shown in Supplementary information, Figure S7F-S7H, we added miR-150, an endogenous mammalian miRNA, into chow diet and fed mice with miR-150-enriched chow diet and normal chow diet, respectively. We found that miR-150 could also enter mouse liver and downregulate its target gene, c-Myb. Given that exogenous miRNAs in food or miRNAs that are ‘added’ into the food can enter the circulation and various organs of animals and play a role in regulating the physiological or pathophysiological conditions, food-derived exogenous miRNAs may be qualified as a novel nutrient component, like vitamins and minerals.
Previous studies have reported that the transfer of genetic material from one species to another may modulate the cellular functions of the recipient species50,51. Such examples include human miRNAs targeting viral genes50 and the translocation of host plant mRNAs into dodder (a parasitic plant)51. However, to our knowledge, it was still unknown whether plant miRNAs could enter mammals and modulate mammalian cell functions. By illustrating that plant miRNAs, such as MIR168a, can be delivered into animal serum and tissues through food intake and digestion and that exogenous MIR168a can target mammalian liver-specific LDLRAP1 in vitro and in vivo, the present study significantly extends our understanding of the role of miRNAs. With their robust stability and highly conserved sequences, secretory miRNAs can act not only in a cross-species, but also a cross-kingdom fashion.
In this sense, miRNAs may represent a novel class of universal modulators that play an important role in mediating animal-plant interactions at the molecular level. Like vitamins, minerals and other essential nutrients derived from food sources, plant miRNAs may serve as a novel functional component of food and make a critical contribution to maintaining and shaping animal body structure and function. Extending from this concept, the intake of certain plant miRNAs generation after generation through a particular food source may leave an imprint on the genetic map of the human race.
In conclusion, the discovery of plant miRNAs and their roles in the biology of mammalian cells and animal organs represents the first evidence of cross-kingdom transfer of functionally active miRNAs and opens a new avenue to explore miRNA-mediated animal-plant interactions.
The anti GM food crowd will little comfort in this study. It shows their fears are self inflicted.