Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Meta-analysis evaluating the association of saturated fat with cardiovascular disease
American Society for Clinical Nutrition ^ | January 13, 2010 | Patty W Siri-Tarino, Qi Sun, Frank B Hu and Ronald M Krauss

Posted on 01/25/2010 10:04:28 PM PST by Coleus

Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease1,2,3,4,5Patty W Siri-Tarino, Qi Sun, Frank B Hu and Ronald M Krauss

1 From the Children's Hospital Oakland Research Institute Oakland CA (PWS-TRMK)the Departments of Nutrition (QSFBH)Epidemiology (FBH) Harvard School of Public Health Boston MA.

2 PWS-T and QS contributed equally to this work.

3 The contents of this article are solely the responsibility of the authors and do not necessarily represent the official view of the National Center for Research Resources (http://www.ncrr.nih.gov) or the National Institutes of Health.

4 Supported by the National Dairy Council (PWS-T and RMK) and made possible by grant UL1 RR024131-01 from the National Center for Research Resources, a component of the National Institutes of Health (NIH), and NIH Roadmap for Medical Research (PWS-T and RMK). QS was supported by a Postdoctoral Fellowship from Unilever Corporate Research. FBH was supported by NIH grant HL60712.

5 Address correspondence to RM Krauss, Children's Hospital Oakland Research Institute, 5700 Martin Luther King Junior Way, Oakland, CA 94609. E-mail: rkrauss@chori.org .

ABSTRACT

Background: A reduction in dietary saturated fat has generally been thought to improve cardiovascular health.

Objective: The objective of this meta-analysis was to summarize the evidence related to the association of dietary saturated fat with risk of coronary heart disease (CHD), stroke, and cardiovascular disease (CVD; CHD inclusive of stroke) in prospective epidemiologic studies.

Design: Twenty-one studies identified by searching MEDLINE and EMBASE databases and secondary referencing qualified for inclusion in this study. A random-effects model was used to derive composite relative risk estimates for CHD, stroke, and CVD.

Results: During 5–23 y of follow-up of 347,747 subjects, 11,006 developed CHD or stroke. Intake of saturated fat was not associated with an increased risk of CHD, stroke, or CVD. The pooled relative risk estimates that compared extreme quantiles of saturated fat intake were 1.07 (95% CI: 0.96, 1.19; P = 0.22) for CHD, 0.81 (95% CI: 0.62, 1.05; P = 0.11) for stroke, and 1.00 (95% CI: 0.89, 1.11; P = 0.95) for CVD. Consideration of age, sex, and study quality did not change the results.

Conclusions: A meta-analysis of prospective epidemiologic studies showed that there is no significant evidence for concluding that dietary saturated fat is associated with an increased risk of CHD or CVD. More data are needed to elucidate whether CVD risks are likely to be influenced by the specific nutrients used to replace saturated fat.

Received for publication March 6, 2009. Accepted for publication November 25, 2009.


TOPICS: Health/Medicine; Science
KEYWORDS: atkins; atkinsdiet; cvd; diet; goodfats; heartdisease; saturatedfat
Navigation: use the links below to view more comments.
first previous 1-2021-28 last
To: Coleus
The source of the "Cholesterol is bad for you" came from a l9l3 Russian study on rabbits.

Cholesterol is a patch material your body manufactures when red bloodcells get damaged by cracked blood vessel walls.

Reduction of dietary Cholesterol actually stresses the body more because it will salvage it from tissue in order to patch those cracks.(Mr. Fit)

Now a real scientist would wonder what causes those cracks in the first place. IOW, what keeps blood vessels flexible and smooth, or what makes them harden and crack?

If the docs in Korea working on those l8-22 year old soldiers had asked that question instead of, "what is this stuff clogging these young arteries?", we wouldn't be asking it now. You see, those l8-22 year olds grew up in the lean years of the great depression. They didn't get something they needed.

What could it be? Think about it for a while I bet you can guess.

21 posted on 01/26/2010 7:31:28 AM PST by PeaceBeWithYou (De Oppresso Liber! (50 million and counting in Afganistan and Iraq))
[ Post Reply | Private Reply | To 1 | View Replies]

To: petro45acp

I have read that the healthiest cooking oil is coconut oil. It is also very expensive.


22 posted on 01/26/2010 7:36:52 AM PST by csmusaret (Right wing extremists: Jefferson, Adams, Madison, Paine, and me.)
[ Post Reply | Private Reply | To 10 | View Replies]

To: Coleus

Now I feel a bit better about the deep fryer I bought last week.


23 posted on 01/26/2010 7:39:54 AM PST by toast
[ Post Reply | Private Reply | To 1 | View Replies]

To: csmusaret

It is, but you want to make sure it isn’t hydrogenated. There is no need to process it like seed or vegetable oils, it is good right out of the pulp, no toxins to cook off, no racidity to perfume and color away, etc.


24 posted on 01/26/2010 8:02:58 AM PST by PeaceBeWithYou (De Oppresso Liber! (50 million and counting in Afganistan and Iraq))
[ Post Reply | Private Reply | To 22 | View Replies]

To: Texas Jack

I eat almost no meat except venison and feral hogs. Last year I even added a roast beaver to the menu (the kind that build dams and eat trees, not the other kind that is normally for desert).

I have to add a bit of beef or pork fat to the Bambi-Burger and pork sausage to improve taste, but it is still a low fat product.


25 posted on 01/26/2010 3:51:24 PM PST by darth
[ Post Reply | Private Reply | To 15 | View Replies]

To: Coleus

Thanks Coleus.


26 posted on 01/26/2010 6:08:44 PM PST by SunkenCiv (Happy New Year! Freedom is Priceless.)
[ Post Reply | Private Reply | To 2 | View Replies]

To: PA Engineer

yes, “metabolic syndrome” and we can also say, “syndrome-x”, “hperinsulinism”, “triglycerides”, and that processed sugars, carbohydrates, concentrated fruit sugar and those “natural foods inculding some fruit and vegetables” that are high on the glycemic index should be avoided.


27 posted on 02/01/2010 10:12:01 AM PST by Coleus (Abortion, Euthanasia & FOCA - - don't Obama and the Democrats just kill ya!)
[ Post Reply | Private Reply | To 16 | View Replies]

To: Coleus

Agreed. I would say the government is culpable for this. There never was a scientific basis for a carbohydrate based diet. This is one of the continued nightmares of government “medicine” as adopted in the food pyramid during the Carter administration. This is also the time that the war on dietary fat began.


28 posted on 02/01/2010 11:19:19 AM PST by PA Engineer (Liberate America from the occupation media.)
[ Post Reply | Private Reply | To 27 | View Replies]


Navigation: use the links below to view more comments.
first previous 1-2021-28 last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson