[VadeRetro]

. But it is the same length as the "good" protein, then "right" does not equal "good" (Which I interpret to signify "right").

A devastating argument against the proposition that getting the length right is one of the big, big hurdles. Do you want to tell gore or shall I?

[AndrewC]

A devastating argument against the proposition that getting the length right is one of the big, big hurdles.

But it is as devastating to random "fitness". Thermodyanmically it would appear as if the prion was the most stable form of the protein.