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When asked to say which is the greatest commandment, Jesus replied:

Matthew 22: 37And He said to him, “’YOU SHALL LOVE THE LORD YOUR GOD WITH ALL YOUR HEART, AND WITH ALL YOUR SOUL, AND WITH ALL YOUR MIND.’ 38”This is the great and foremost commandment. 39”The second is like it, ‘YOU SHALL LOVE YOUR NEIGHBOR AS YOURSELF.’

If we do not observe this commandment, if we do not love God, or do not love our neighbor, do we sin?

odd way to turn upside down what I offered, but the answer is, we love The Lord Our God because We are in His family. We learn to love our neighbor as our selves. Romans 8 says:

1 Therefore, there is now no condemnation for those who are in Christ Jesus, because through Christ Jesus the law of the Spirit who gives life has set you free from the law of sin and death. For what the law was powerless to do because it was weakened by the flesh, God did by sending his own Son in the likeness of sinful flesh to be a sin offering. And so he condemned sin in the flesh, in order that the righteous requirement of the law might be fully met in us, who do not live according to the flesh but according to the Spirit.
Those who live according to the flesh have their minds set on what the flesh desires; but those who live in accordance with the Spirit have their minds set on what the Spirit desires. The mind governed by the flesh is death, but the mind governed by the Spirit is life and peace. The mind governed by the flesh is hostile to God; it does not submit to God’s law, nor can it do so. Those who are in the realm of the flesh cannot please God.

Once born from above you are no longer living according to the laws of sin and death. Do you fail to be the perfect child of His family? Of course, we still have the Adamic inheritance. But we learn to walk not after that flesh, by allowing His life in us to teach us the Way that we should go.