One only has to look at the same scene as recorded in Luke 22 to see that Jesus was fulfilling the Passover cups of wine not blood (there are 4, and Jesus did not drink the last but will in the Kingdom). To insist that the words recorded in John and Matthew somehow have Jesus telling these Jewish men to drink His blood would mean the sentence by Jesus in Luke's telling, 'This cup is the new covenant' would fit an Indiana Jones movie, not the introduction of a sacrament to be repeated in REMEMBRANCE of His sacrifice for us. RCC insists each Mass is a repeat of the sacrifice with the 'real and substantial body and blood and soul and divinity of The Son of God Who is in Haven at the right hand of the throne of God Almighty.
Luke 22: 14And when the hour come, he reclined (at meat), and the twelve apostles with him, 15and he said unto them, With desire I did desire to eat this passover with you before my suffering, 16for I say to you, that no more may I eat of it till it may be fulfilled in the reign of God. 17And having taken a cup, having given thanks, he said, Take this and divide to yourselves, 18for I say to you that I may not drink of the produce of the vine till the reign of God may come. 19And having taken bread, having given thanks, he brake and gave to them, saying, This is my body, that for you is being given, this do ye to remembrance of me. 20In like manner, also, the cup after the supping, saying, This cup [is] the new covenant in my blood, that for you is being poured forth.
In the World English Bible that last sentence has Jesus pouring the contents out not passing it for drinking, signifying His blood was about to be shed, poured out for them and us.
Luke 22: 17And having taken a cup, having given thanks, he said, Take this and divide to yourselves, 18for I say to you that I may not drink of the produce of the vine till the reign of God may come. 19And having taken bread, having given thanks, he brake and gave to them, saying, This is my body, that for you is being given, this do ye to remembrance of me. 20In like manner, also, the cup after the supping, saying, This cup [is] the new covenant in my blood, that for you is being poured forth.
You put on the table perhaps the most disputed theological issue between Catholics and Protestants. I decline to get drawn into a bottomless swamp of disputation over the nature of the Catholic Eucharist.