At least 500!
After that, [Jesus] appeared to more than five hundred brothers at the same time, most of whom are still living, though some have fallen asleep." 1 Cor. 15:6 Because of the Bibles broad semantic use of brother, we can be confident that Mary did not give birth to more than 500 children.
Also, look at Genesis 13:8. The word brother is being used to describe the relationship between Abraham and Lot, who were not biological brothers but uncle and nephew: So Abram said to Lot, Lets not have any quarreling between you and me, or between your herdsmen and mine, for we are brothers (Gen 13:8).
The term 'brother' as used in the Bible has a broader meaning than uterine brothers. It can mean a biological brother, but it can also mean an extended relative, or even a spiritual brother.
In the Bible, these 'brothers' of Jesus are never once called the children of Mary. Only Jesus himself is called the child of Mary.
Luke a medical doctor wrote Luke 2:7 And she brought forth her firstborn Son, and wrapped Him in swaddling clothes, and laid Him in a manger; because there was no room for them in the inn.
Luke as a medical doctor would know the difference in ‘first’ born and ‘only’ born. Get prepared to find out Mary was a loving wife to Joseph and had other live birth children. Why is there a made up exemption for Mary to practice birth control????????
No it can't...A natural brother or a spiritual brother, ok...An extended relative, Nope, in the New Testament...