The oppression did not start until after the Protestant Reformation had started.
Your tyrannical persecution of the Jews, though not in Rome mostly in Spain, took place before the Protestant Reformation. I'm sure you've heard of the Inquisition. You choice of words, "oppression" is more spin. Burning people at the stake is worthy of stronger language than mere "oppression."
The tyrannical persecution did not happen in Rome, where the Church would have no temporal difficulty. Why did it not happen in Rome?