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During the Reformation, in 1555, Pope Paul IV decreed that all Jews must be segregated into their own quarters (ghettos), and they were forbidden to leave their home during the night, were banned from all but the most strenuous occupations and had to wear a distinctive badge a yellow hat. More than 4,700 Jews lived in the seven-acre Roman Jewish ghetto that was built in the Travestere section of the city (which still remains a Jewish neighborhood to this day) If any Jews wanted to rent houses or businesses outside the ghetto boundaries, permission was needed from the Cardinal Vicar. Jews could not own any property outside the ghetto. They were not allowed to study in higher education institutions or become lawyers, pharmacists, painters, politicians, notaries or architects. Jewish doctors were only allowed to treat Jewish patients. Jews were forced to pay an annual stipend to pay the salaries of the Catholic officials who supervised the Ghetto Finance Administration and the Jewish Community Organization; a stipend to pay for Christian missionaries who proselytized to the Jews and a yearly sum to the Cloister of the Converted. In return, the state helped with welfare work, but gave no money toward education or caring for the sick. These anti-Jewish laws were similar to those imposed by Nazi Germany on the Jews during World War II.