Have at it boys.
You can’t prove a negative.
It's really the anti-intellectual position that readily embraces the idea that there is no reason for existence. What existed before the ‘big bang’, if indeed the big bang theory is definitively accurate? Are the ‘laws’ of physics, which humans formulated to explain what we observe of the universe, immutable? Are they the same everywhere? How many times in the future will ‘laws’ have to be revised to explain new observations/new phenomena? Anyone who says something as stupid as claiming to be able to prove God doesn't exist doesn't qualify as a scientist in my book.