One of those hard sayings. Words mean things. I thought that the plain sense was to be considered the most likely correct interpretation. At least, that is what I was taught by my sola teachers.
No, that's not the way the word of God tells us God interacts with us. God is spirit, and He reaches men spiritually.
That's what the "plain sense" of Scripture tells us.
For to be carnally minded is death; but to be spiritually minded is life and peace. Because the carnal mind is enmity against God: for it is not subject to the law of God, neither indeed can be. So then they that are in the flesh cannot please God. But ye are not in the flesh, but in the Spirit, if so be that the Spirit of God dwell in you. Now if any man have not the Spirit of Christ, he is none of his. And if Christ be in you, the body is dead because of sin; but the Spirit is life because of righteousness. But if the Spirit of him that raised up Jesus from the dead dwell in you, he that raised up Christ from the dead shall also quicken your mortal bodies by his Spirit that dwelleth in you." -- Romans 8:5-11"For they that are after the flesh do mind the things of the flesh; but they that are after the Spirit the things of the Spirit.
Carnally-minded = death.
Spiritually-minded = life and peace.