Some do and some don't. Amoebas have a genome many times the size of the human genome. There are bacteria having essentially zero non-coding genetic material. Mitochondria have genetic material that is very resistant to change.
It is simply counterfactual to assert that living things devolve due to entropy.
[[It is simply counterfactual to assert that living things devolve due to entropy.]]
None of which you mentioned argues that species are not subject to entropy