At one point, when the dipsy sister asks Joe if he's ever thought of killing himself.
JOE: What? Why would you do that? ANGELICA: Why shouldn't I? JOE: Some things take care of themselves. They're not your job. Maybe they're not even your business. I always liked those lines. ANGELICA: Did you ever think aboout killing yourself?
It is indeed a great story about courage in surrendering to God's will - and the futility of worry.
In the last scene (I forgot the exact words) but she says something to Joe like "it's always going to be something with you, isn't it?" LOLOL!