Though not a shrine in honor of canonized Saints, also of note in the Czech Republic is "Sedlec Ossuary" ("Kostnice")...The man who created the monstrance of bones (see below) was a man of great faith.
I am the bread of life. Your forefathers ate the manna in the desert, yet they died. But here is the bread that comes down from heaven, which a man may eat and not die. I am the living bread that came down from heaven. If anyone eats of this bread, he will live forever. This bread is my flesh, which I will give for the life of the world. (John 6:48-51)
Unfortunately, this is a case that local officials would not give the Capuchins any more land to bury their monks, so they came up with a way of creating a church filled with the bones of the Capuchins...
It is rather bizarre, but it is similar to what the Germans did to the Jews (circa 1600's and 1700's) refusing the Jews additional space to bury their dead.
The bone church is in Italy...