The worst possible thing for her is to be seen as a loser.
If people begin to realize that she is not the political miracle worker and king-maker she pretends to be, she will become a political irrelevancy almost instantly. Her enemies will come after her with a vengence, and her friends will cut her loose in a heart-beat. The only reason anybody works with Hilllary! at all is that they all think that she will be President some day, and they fear incurring her wrath. Once it becomes obvious that she has gone as high as she will go, the sharks in the water will begin to feed, and she will learn that she has no true friends to save her.
Fortunately, people are beginning to see that Hillary! has the smell of a loser. Mark Green, Andrew Cuomo, and Janet Reno (after today) can all attest to that. Including Reich, the Clintonistas are 0-4 since 1/21/01. Their political impotence is becoming obvious to all.
Not to be a party-pooper, but y'all are forgetting that Clintonista guy in Chicago...
But...you're right enough! Based on the "statistics", the "little Clintons" are not looking good, and it will be so much more fun when the Clintons themselves are finally and duly gone!!
This will be more difficult to accomplish, but I have complete confidence and faith that it will happen, hopefully sooner rather than later...