The banning of CFC's has come at great societal cost. We took a huge step backwards in energy efficiency of air conditioning / refrigeration equipment as a result of the transition to the new refrigerants. Thank you, enviralmentalist whackos. < /sarcasm>
I still have a *big* tub of R-22 for my home systems.
People forget Icehouses were always located at th edge of town for a good reason in pre-Freon days- leaks of ammonia or the other common refrigerant gases were poisonous! Unless you overheat it ( phosgene! ) Freon is one of the most inert substances you will find.