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Ritalin May Change Brain Long-Term, Study Shows
Reuters News Service ^ | November 11, 2000 | Reuters Staff

Posted on 11/12/2001 5:15:21 PM PST by t-shirt

Ritalin May Change Brain Long-Term, Study Shows

Sunday November 11 2001

WASHINGTON (Reuters) - The stimulant Ritalin (news - web sites), a drug used to help children with attention deficit hyperactivity disorder, may cause long-term changes in the brain, researchers reported Sunday.

The changes look similar to those seen with other stimulants such as amphetamine and cocaine, at least in rats, the team at the University of Buffalo found.

``Clinicians consider Ritalin to be short-acting,'' Joan Baizer, a professor of physiology and biophysics who led the study said in a statement.

``When the active dose has worked its way through the system, they consider it 'all gone.' Our research with gene expression in an animal model suggests that it has the potential for causing long-lasting changes in brain cell structure and function.''

But Baizer said that Ritalin, known generically as methylphenidate, probably is not addictive in the way drugs of abuse are if it is used properly.

``Children have been given Ritalin daily for many years, and it is extremely effective and beneficial, but it's not quite as simple as a short-acting drug,'' she said. ``We need to look at it more closely.''

High doses of amphetamine and cocaine have been found to switch on genes known as ``immediate early genes'' in brain cells. One of the genes, called c-fos, has been linked with addiction when it is activated in certain parts of the brain.

The researchers gave rat pups sweetened milk carrying methylphenidate in comparable doses and at similar times to what a child would get.

C-fos genes were activated in their brains in a pattern similar to that seen in cocaine and amphetamine use, the researchers told a meeting of the Society for Neuroscience in San Diego.

``These data do suggest that there are effects of Ritalin on cell function that outlast the short term and we should sort that out,'' Baizer said.

She said perhaps a gene chip -- a microarray -- could be used to see just which genes are turned on and off by methylphenidate.


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Get your kids off this crap!

Be sure to get this info out far and wide!

1 posted on 11/12/2001 5:15:21 PM PST by t-shirt
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To: Mercuria; archy; Freeper; FormerLurker; The Documentary Lady; freedomson; Angelique...
bump
2 posted on 11/12/2001 5:18:33 PM PST by t-shirt
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To: t-shirt
Only science would not think that a drug that alters your brain chemistry would not have lasting effects on your brain chemistry.
3 posted on 11/12/2001 5:18:58 PM PST by DouglasKC
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To: mlo
No doubt this study had government funding behind it. Therefore, you must ask yourself....how can we be sure it isn't all a lie? It could also be a part of the WOD as they try to keep us from the good stuff, eh?

I'm sorry, I just can't help myself. Is there a full loon out tonight? Seems FR is full of it today!

4 posted on 11/12/2001 5:25:38 PM PST by anniegetyourgun
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To: t-shirt
None of that sh^t will be used on any of my kids, and like Stone Cold Steve Austin says, "dat's all I gotta say 'bout that!"
5 posted on 11/12/2001 5:29:03 PM PST by Dan from Michigan
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To: t-shirt
This is an important article. It could easilly get buried. I never trusted mass ritalin use by highly active kids.
6 posted on 11/12/2001 5:37:42 PM PST by Arthur Wildfire! March
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To: t-shirt
Are you kidding!! Parents love ritalin, makes it easy so they won't have to be parents. Just like TV, it's the best baby sitting tool known to man. Throw away the TV then someone might have to actually be a parent for a change.

Ritalin will always be around, it's the easy way out and convenient. Most ADHD is due to allergies, diet related, etc. Can be controlled but it takes TIME and WORK.

Try a little corporal punishment in the schools and you will see how fast their hyperactivity stops.

What happens when the child becomes an adult? Hyperactivity goes away like magic? That's because they never had it.

Ritalin = cocaine, when child becomes an adult Ritalin is stopped and cocaine addiction usually starts.

7 posted on 11/12/2001 5:38:41 PM PST by Coleus
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To: anniegetyourgun
Do ever bother obeying any of Free Republic's rules or are you allowed to roam around thread to thread with you personal attacks and disrupting?

I can't believe spent several minutes posting you a long reply a little while ago to you tonight. You should be ashamed of your behavior.

8 posted on 11/12/2001 5:40:07 PM PST by t-shirt
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To: DouglasKC
I bet I know what you are thinking. The old saying, "Follow the money, sonny." Considering a dope head tied with the mob was in charge of the executive branch for the last eight years, I wonder who led the 'green light' conclusion to the ritalin policy, and which of Bubba's friends got rich from it.
9 posted on 11/12/2001 5:40:51 PM PST by Arthur Wildfire! March
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To: anniegetyourgun
I'm sorry, I just can't help myself. Is there a full loon out tonight? Seems FR is full of it today!

"And the loon spun round like a top..."

10 posted on 11/12/2001 5:41:09 PM PST by Elenya
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To: t-shirt
Why because she doesn't subscribe to your hysteria about the bogeyman being under your bed? Put me in annie's corner, I've had enough of YOUR nonsense.
11 posted on 11/12/2001 5:42:27 PM PST by Trust but Verify
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To: t-shirt
ADD Attention Deficit Disorder......The attention that is in deficit is that of the parents to the child. Saw it happen several cases. End of story.
12 posted on 11/12/2001 5:42:48 PM PST by Lower55
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To: t-shirt
Get your kids off this crap! Be sure to get this info out far and wide!

And then what? Seriously? I will say Ritalin is over prescribed and ADD ADHD is Highly Misdiagnosed Not Over Diagnosed. A true ADD ADHD kid or ADHD adult will benefit from Ritalin. Many more though are not and Ritalin is of no value. There are many simuliar disorders that fit ADD ADHD behavioral patterns and in fact are not ADD ADHD.

Make the shrink the last stop. Make an Audiologist one of the first after the family GP. Sensory Processing Disorders probably account for the high percentage of ADD ADHD diagnoses increases we now see. The reason being is there are now far more triggering devices for these disorders than there was in the pre 1980's. A child or adult with medical histories of allergies or chronic ear infections are prime canidates for these type disorders. They are treatable in such that you treat the damaging cause to limit further problems.

13 posted on 11/12/2001 5:44:40 PM PST by cva66snipe
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To: Trust but Verify
Why because she doesn't subscribe to your hysteria about the bogeyman being under your bed?

I posted a an important and serious story about a scientific study done by a respected American University and annie comes on with personal attacks on me and others in violation of FR rules, which is shameful behavior just like yours. And then you come on like the clown you apparently are and talk about a bogeyman under your bed. Can you try to act like a man instead of like a child misbehaving in a chatroom?

14 posted on 11/12/2001 5:51:48 PM PST by t-shirt
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To: t-shirt
Sorry, ts....I didn't know you were in charge of this thread. I'll not bother you anymore.
15 posted on 11/12/2001 5:55:20 PM PST by anniegetyourgun
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To: t-shirt
get your kids off of this crap

i agree. seems that the public schools are pushing this. guidance counselors and school psychologists put the bug in parents' ears. is it to help the kids? or is it to make the lives of the public school teacher easier?
16 posted on 11/12/2001 5:55:52 PM PST by mlocher
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To: t-shirt
The United States Military will not accept anyone who has been on Ritalin once they have reached puberty. Guess they have known for a long time just how dangerous this drug is.
17 posted on 11/12/2001 5:57:55 PM PST by OldFriend
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Comment #18 Removed by Moderator

To: OldFriend
The United States Military will not accept anyone who has been on Ritalin once they have reached puberty. Guess they have known for a long time just how dangerous this drug is.

Yes and there is a good reason but not what you think though. They do not keep you out due to the Ritalin. They keep you out because the Ritalin usage requirement says a condition that requires it's usage is still there. It didn't leave at puberty. Meaning probable sensory problems. I passed two military physicals while only having vision in one eye at a time. That is a sensory problem. At the same time I was diagnosed in early childhood in mid 1960's with ADHD. I did not have it and my reaction to Ritalin pointed to that fact.

These type problems can mean anything from no depth perception to inability to properly hear and understand orders. The Ritalin usage is a flag for a underlying Neurological condition and nothing more. That is the big secret the military understands about Ritalin usage.

19 posted on 11/12/2001 6:08:51 PM PST by cva66snipe
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To: OldFriend
The United States Military will not accept anyone who has been on Ritalin once they have reached puberty.

Are you sure about that? I know of a young man who took Ritalin in High School (and that is in his public school records because I remember his mom worrying about that) and not sure if he is still taking Ritalin, but he was accepted in the army, doing well and just finishing boot camp.

20 posted on 11/12/2001 6:09:42 PM PST by mostlyundecided
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