Most of the federal drug legalization folks rest their belief on freedom and the Constitution.
The same human right to self-determination that stood athwart forced vaccination is the same right in this case.
Where in the Constitution is the state empowered to band pot etc? And before you say the Commerce Clause, remember it required an amendment to ban booze.
To argue for Leviathan to be empowered to ban drugs is to give a cheery two thumbs up to forced vaccination and forced euthanasia and other “your body are belong to us” sentiments. Welcome to North Korea.
We are thinking human beings with the Constitution in our hands. If we really are thinking, we'll severely curtail or ban destructive substances, especially when we have ample evidence of their destructive natures.