Because she’s running for Senate this year, she’s presumably busy with that campaign.
And depending on state law in Arizona ,she might not be able to be a candidate for vice president and Senate on the same ballot in the same year.
Rubio is Cuban, so I don't know if non-Cuban Hispanics would be especially inclined to vote for him. He isn't the worst of the names that have been thrown out, but he isn't the best choice.