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It is sort of a "platform vs. publisher" argument...he ran the "Silk Road" platform...others sold the drugs. (I didn't look up the evidence in the case, but I think the argument is that he was not "dealing", just running the "marketplace").
Trump has promised to commute his sentence. He’s been in jail for 11 years. So maybe out after 12. There were claims that he directed murders, plus the drug deals, and more. A bad guy.
I see no difference. He was facilitating the sale of drugs, enriching drug dealers/cartels at the expense and endangerment of others.