He was asked the question facing an impending re-election campaign.
Did anyone think he would answer, "Well, first I want to get re-elected so I can focus on a presidential campaign."
Charlie Crist would've clobbered him with the allegations that Ron DeSantis doesn't really want to be governor of Florida.
Point is, at no time did DeSantis EVER say he would defer running in case Trump wanted to jump into the race. And in September '21, Trump was more than a year out from declaring.
As stated earlier, we all knew Trump would run again.