I have personally been to LEF farms in Loudon, NH.
https://www.brightfarms.com/farms/new-hampshire/
This is a fully automated hydroponic greenhouse operation in central NH. They grow lettuce. They package it and sell it to grocery stores.
This is what I like about it. There are NO illegal aliens employed to pick the lettuce and package it. The space it takes up in relation to its yield/acre is relatively small.
They grow it year round 24/7. There is never any ecoli contamination. It is never touched by human hands prior to packaging. It ships to the store from less than a couple hundred miles away to most destinations. It is not being shipped from Chile in the winter or Mexico or Florida or California.
At least BrightFarms lettuce does see the sun. One has to wonder if the lack of soil microorganisms has any effect on nutrition. How does sterile food affect gut flora/microbiota?
I guess like margarine, lead, we'll find out if it's good or bad in some decades.