VP Harris was elected so the only way she leaves office is if she dies, resigns of is impeached. She’s healthy so she is not about to die. No one is talking impeachment so that leaves a bribery. I think it would take a really good bribe to get her to resign.
There is talk about a SC seat but I seriously doubt she could get 60 votes in the Senate.
Not unless McConnell and et al are promised something they want really bad. Knowing McConnell it wouldn't be surprising.