What’s Happening With Johnson & Johnson’s Covid-19 Vaccine Rollout?

I’ve also been holding out for the J&J vaccine for a couple reasons. It’s only one shot and also it’s not using mRNA. Our local Walmarts are getting them in this week so I signed up online and will get it Thursday. It specifically said it was the J&J shot.

RE: Which vaccines use the traditional (dead/deactivated virus) approach to vaccines (not the mRNA).

J&J’s vaccine uses a deactivated Adenovirus for their vaccine.

Apparently, so does Novavax’s

Pfizer now claims their vaccine is 90% efficient at stopping the virus. If everyone in the country were to be vaccinated, 331 million, according to Pfizer we should expect 33 million to contract the virus, correct? The first year of Covid saw 30 million cases in the USA with no vaccine. Call and get those vaccine appointments! Hurry!!!!!!

I understand COVID-19 didn’t exist then. I stated the coronavirus which has been around forever. I have read multiple articles stating for decades a vaccine for the coronavirus was a pipedream. I was just curious what change occurred with COVID-19 that allowed the decades old tech from J&J to work now and not then.

Well, a vaccine against ‘coronavirus’ in general is one of those things like ‘a cure/vaccine against all cancer.’ For one, ‘coronavirus’ is a class or type name for a number of viruses that all have the same general appearance under the microscope. The actual individual members of the class are all different (like all cancers are different, or all pickup trucks are different but still members of the same class) and so their treatment and prevention is, at this stage of medical science, going to be different for each one. Medical science hopes and tries for a blanket solution, but it doesn’t look like we’re going to get one anytime soon. In the meantime, treatment/vaccine development proceeds one virus (and one form of cancer) at a time.

With newer tools and better research, this technology and others *have* achieved some success in the past 10-20 years against some Corona viruses and some cancers. For example, we now know that human papilloma virus causes cervical, tonsil and genital cancer and a vaccine was developed to prevent that. We (as in humanity) also have developed vaccinations against hepatitis A and B, some forms of meningitis, some forms of bacterial pneumonia, and many forms of rotavirus in the last 20 years - and the list goes on. There may soon be a vaccination against type I diabetes, which was an outgrowth of anti-rotavirus research.

Just following up - late that night, I started feeling anticipated side effects. Bit of a headache, general low intensity body aches, some fatigue, slight fever. Pretty much SOP when viruses invade and the immune system identifies that there’s an intruder.

This is actually *good* news, though - this means that my immune system hasn’t previously been exposed to human adenovirus 5, the pithed carrier virus for for the COVID-19 proteins, and it’s going to war against the new threat it’s spotted. All the above symptoms are caused not by the virus but by the immune system in my case - some people do not have this happen and their system still works just fine, others have worse responses and it even varies by vaccine. A reaction on this scale (for me) tends to indicate that the immune system won’t forget what the threat ‘looks like’ any time soon. In this case (to use an oversimplification,) this AD5 virus dose has been the equivalent of painted and mocked up to look like COVID-19 to the immune system; once my immune system takes them apart, it will know that if it “sees” something that looks like it, it can kill it immediately with a pre-prepared response instead of going to war and trying to figure out what it is and how to attack it.

Or put another way, basically the Johnson & Johnson vaccine trains the immune system with inert practice targets.

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