The fly in the ointment is that mRNA is never supposed to get outside a cell. It exists in the nucleus or the cytoplasm. What becomes of mRNA that fails to find its way inside a host cell? Exogenous mRNA deposited by injection is a fairly new technique. The intended action is for the mRNA to make its way inside a cell and leverage the cell machinery just as a virus does. The beta test for what happens in large populations is underway.
Covid variant VUI – 202012/01.
“Here you come again
Just when I’ve begun to get myself together
You waltz right in the door, just like you’ve done before
And wrap my heart ‘round your little finger”
Plans are to delay the second shot of the 2-dose vaccines and instead concentrate on getting the first shot to more people.
In a discussion, the key point made for this change in plans is “6/ If one instead looks at the day 10 to day 22 period one instead gets an efficacy value of 86% (there will be confidence intervals around that). “
https://twitter.com/theosanderson/status/1344347380917940226
We’ll learn a lot from this experiment.
On reflection I’m not too worried about this mRNA vaccine.
But what future uses will the tech be put to?
If you can tell a cell to do one thing then you can tell it to do others- maybe terrible things.