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To: gas_dr

You are incorrect. ARDS can be cause by any viral agent. You are higher risk with more comorbidities.


I agree with the latter two of those things, and have posted references to those things myself.

I have seen an awful lot of non CoVId cases in my time influenza and other respiratory tract infection where the risk is heart disease and leads to the exact same pathology and pathophysiology.


Are you saying that in your experience this applies often even where you have non-respiratory presentations? More than the occasional, and where hypertension is mild, under control, or has receded and is no longer evident even without further treatment? I am indeed aware that with the more severe cases of high blood pressure that most any stressor can push them over the edge, but this appears to go well beyond that.


94 posted on 04/06/2020 6:47:49 AM PDT by lepton ("It is useless to attempt to reason a man out of a thing he was never reasoned into"--Jonathan Swift)
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To: lepton

You know, I honestly dont know. I am perplexed by the connection with HTN. I know there is some connection with Angiotensin and the renal - angiotensin - aldosterone axis, but I am unsure if it is related to the uncontrolled presence of ACE or actually the ACEi therapy — I read speculation on both. Honestly, I do not think we are sophisticated enough to know all the variables on this?

This is the perfect extrapolation for the bench scientists to figure out. So, I have no ability to take a stab at this as I know what I dont know, and I surely dont have an answer for this. I am sure there are some people far smarter than me who can answer this. My gut feeling, though, is that it has to do with the presence of the ACE inhibitors. But that is pure conjecture and should not be taken as anymore than the guess that it is.


127 posted on 04/06/2020 7:34:16 AM PDT by gas_dr (Trial lawyers AND POLITICIANS are Endangering Every Patient in America: INCLUDING THEIR LIBERTIES)
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