Posted on 04/03/2020 11:40:54 AM PDT by SeekAndFind
On Saturday the Food and Drug Administration approved the use of two antimalarial drugs, hydroxychloroquine and a related medication, chloroquine, for emergency use to treat COVID-19. The drugs were touted by President Trump as a “game changer” for COVID-19.
However, a study just published in a French medical journal provides new evidence that hydroxychloroquine does not appear to help the immune system clear the coronavirus from the body. The study comes on the heels of two others - one in France and one in China - that reported some benefits in the combination of hydroxychloroquine and azithromycin for COVID-19 patients who didn’t have severe symptoms of the virus.
I am a medicinal chemist who has specialized in discovery and development of antiviral drugs for the past 30 years, and I have been actively working on coronaviruses for the past seven. I am among a number of researchers who are concerned that this drug has been given too much of a high priority before there is enough evidence to show it is indeed effective.
There are already other clinical studies that showed it is not effective against COVID-19 as well as several other viruses. And, more importantly, it can have dangerous side effects, as well as giving false hope. The latter has led to widespread shortages for patients who need it to treat malaria, lupus an rheumatoid arthritis, the indications for which it was originally approved.
The idea that the combination of hydroxychloroquine with an antibiotic drug, azithromycin, was effective against COVID-19 gained more attention after a study published on March 17. This study described a trial of 80 patients carried out by Philippe Gautret in Marseille, France. Although some of their results appeared to be encouraging, it should also be noted that most of their patients only had mild symptoms.
(Excerpt) Read more at news.yahoo.com ...
Here is that other French Study for those who are interested in reading it:
https://www.sciencedirect.com/science/article/pii/S0399077X20300858?via%3Dihub
TITLE: No Evidence of Rapid Antiviral Clearance or Clinical Benefit with the Combination of Hydroxychloroquine and Azithromycin in Patients with Severe COVID-19 Infection
And many more studies have pointed at its efficacy.
Yahoo news.
Almost always wrong.
Always leftist.
Oh well, it does satisfy at least a couple of readers.
CCP Agiprop?
How about on the next fund drive the FR get a damn post edit feature, uggh
A second French group, led by Jean-Michel Molina, has now tested the hydroxychloroquine-azithromycin combination treatment in 11 patients at the Hôpital Saint-Louis in Paris, France, and their results were strikingly different.
Like the Marseille study, the Molina trial was also a small pilot study. Molina and colleagues used the same dosing regimen as Gautret. In contrast, however, to the Gautret study, eight of the 11 patients had underlying health conditions, and 10 of 11 had fevers and were quite ill at the time the dosing began.
These Paris researchers found that after five to six days of treatment with hydroxychloroquine (600 mg per day for 10 days) and azithromycin (500 mg on day 1 and 250 mg on days 2 to 5), eight of the 10 patients still tested positive for COVID-19. Of these 10 patients, one patient died, two were transferred to the ICU and another had to be removed from the treatment due to serious complications.
In addition, a similar study in China also showed no difference in viral clearance after seven days either with or without the hydroxychloroquine with the patients in the trial. This supports Molina’s findings.
Thus, despite the recent approval of this drug for use against COVID-19, questions remain as to the efficacy of this treatment. As Molina and colleagues note: “Ongoing randomized clinical trials with hydroxychloroquine should provide a definitive answer regarding the alleged efficacy of this combination and will assess its safety.”
It’s really remarkable. Americans demanding the government give them a drug on the basis of reports from China. Who would have ever thought?
But, we WANT it to work. Trump said it would work! “They” said we don’t need to test any more!
//sarcasm.
This is why there are processes for this stuff.
GRRRR!!! WTF IS IT WITH THE MEDIA AND THAT ONE FRENCH STUDY???
It measured death rates in a poll of 30 patients, and found that HCQ was not more effective than the standard treatment, which yields a 97% cure rate (29/30). DESIGNED TO FAIL. How do you significantly improve on 29/30? 45 out of 30?
Typical BS from Yahooooo
Trump-backed anti-malaria drug hydroxychloroquine is the most effective coronavirus treatment currently available, finds international poll of 6,000 doctors
That is my understanding also. It seems like the test are only on last resort patients. No drug will ever stop the horrendous effect that late stage Covid 19 does to the lungs.
Not surprised that the hydrochloroquine doesn’t clear the virus from the body. That would take antibodies that you have to grow yourself. The med is good at reducing the symptoms while your body builds antibodies to fight the virus, and that’s enough.
Good ...don’t use them. More for us. No Trump drugs for liberals.
They are giving it too late to patients, it is supposed to be given as soon as symptoms show up.
i second that request- I’m always doing typos- postign to wrong threads (Because i have several threads open at ocne, and post to wrong one l ol) etc
Couldn’t care less what France says. Tell me what Harvard,Columbia,Hopkins,Mayo Clinic and Stanford say.
This article is Yahoo bs. Trump never declared the drug a game changer. He said it could be IF it works.
Further, my antenna already is up that this study involved “clearing the virus from the bloodstream”. Important I’m sure but not the same as studying relief of symptoms.
I’m finding this virus situation is bringing out the evil in many many people. This article has a political spin.
So one test gave it to people who were still alive and found it effective while the other test gave it to dead people and found they were still dead after giving the drugs.
Have I got that right?
Interesting. Very interesting.
“It’s really remarkable. Americans demanding the government give them a drug on the basis of reports from China. “
^Where does this site find people this stupid and utterly dishonest?
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