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Duke to spearhead $50 million research effort to test hydroxychloroquine in preventing COVID-19
Duke Chronicle ^ | April 2 2020 | Carter Forinash

Posted on 04/02/2020 10:10:43 AM PDT by rintintin

Up to $50 million has been approved for new research on a potential COVID-19 treatment, and Duke is taking charge.

The Patient-Centered Outcomes Research Institute, a federal government-sponsored nonprofit that funds studies across a variety of types of research, announced a new program April 1 to research hydroxychloroquine, most commonly used as an anti-malaria drug, as a way to prevent COVID-19 infections for high-risk healthcare workers. The program will be led by a Duke research team at the Duke Clinical Research Institute, which is part of the School of Medicine.

(Excerpt) Read more at dukechronicle.com ...


TOPICS: Culture/Society
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1 posted on 04/02/2020 10:10:43 AM PDT by rintintin
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To: rintintin

Maybe Nonprofit but certainly VERY LUCRATIVE.


2 posted on 04/02/2020 10:12:46 AM PDT by House Atreides (It is not a HOAX but it IS A PRETEXT!)
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To: rintintin

It could have been more but they had to fund NPR/PBS and the Kennedy Center.


3 posted on 04/02/2020 10:13:16 AM PDT by Drango (1776 = 2020)
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To: rintintin

Boy, for an “anecdotal” “untested” “no evidence that it works” approach, there sure seems to be a lot of interest. How much of this would have happened this quickly had President Trump not spoken up?


4 posted on 04/02/2020 10:14:04 AM PDT by PlateOfShrimp
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To: rintintin

Our hospital has a couple dozen people with the virus. About half dozen on respirators. We’ve discontinued hydroxychloroquine + z-pak because of the cardiac issues it might cause, and most think it’s not helping anyway. Not my decision, but this may not turn out to be the miracle chemicals they anticipated.

Also, we’re hunkering down, and expecting this to peak in mid May, with the hospital full of these patients.


5 posted on 04/02/2020 10:14:16 AM PDT by nikos1121
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To: rintintin

I would be nice to know the dosages that will be given. I’ve seen too many tests that were designed to fail.


6 posted on 04/02/2020 10:16:10 AM PDT by aimhigh (THIS is His commandment . . . . 1 John 3:23)
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To: rintintin

Good Lord, how many of these studies do we need? Seems like we are beyond wasteful and duplicative now.

The University of Minnesota started the same study about three weeks ago.

Why don’t these universities get together and collaborate? (Yeah, I know, dumb question)


7 posted on 04/02/2020 10:18:09 AM PDT by ProtectOurFreedom
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To: Drango

Worse, 20% of the Kennedy Center money flowed back to Dems.


8 posted on 04/02/2020 10:18:57 AM PDT by ProtectOurFreedom
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To: rintintin

50 million to study something everyone already knows?


9 posted on 04/02/2020 10:19:22 AM PDT by JPJones (More Tariffs, less income tax.)
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To: rintintin

I sure don’t know how this stuff works.

For one thing, the drug is now being given to thousands of patients. A real world test. I assume pretty solid conclusions could be drawn from the outcomes.

But I suppose they also want double blind formal experiments so that they can make definitive statements about the efficacy. But $50M???

I have a hard time believing that this is simply the cost of doing business. You know what you’re looking for. You basically know what the answer is (based on real world outcomes). All you’re really doing is gathering documentation. $50M???


10 posted on 04/02/2020 10:19:24 AM PDT by ClearCase_guy (If White Privilege is real, why did Elizabeth Warren lie about being an Indian?)
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To: nikos1121

That sure seems to be contrary to most other hospital findings. Why the different outcomes?

Where is your hospital?


11 posted on 04/02/2020 10:20:11 AM PDT by ProtectOurFreedom
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To: ClearCase_guy

$1 M for the study.
$49 M for shiny new labs.

It does seem like a preposterous number, doesn’t it?


12 posted on 04/02/2020 10:22:12 AM PDT by ProtectOurFreedom
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To: nikos1121

Were they also giving patients zinc with the hydroxychloroquine? Anybody with a zinc deficiency or under a certain level of extracellular zinc is not going to gain the total benefit of hydroxychloroquine. The drug is a zinc ionophore which transports the zinc through the cell membrane and prevents the virus from hijacking the RNA sequencing mechanism of the cell to replicate itself.

If patients didn’t have enough zinc in their system, again, it’s not going to work as well.


13 posted on 04/02/2020 10:23:12 AM PDT by PresidentFelon
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To: All
Hydroxychloroquine, which was recently touted by President Donald Trump as a potential coronavirus treatment

This phrase is repeated verbatim in just about every hydroxychloroquine-related article.
14 posted on 04/02/2020 10:24:34 AM PDT by mmichaels1970
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To: nikos1121
We’ve discontinued hydroxychloroquine + z-pak because of the cardiac issues it might cause

Are the dosages different than used for the treatment of malaria? Hasn't this been used for decades for treating malaria and deemed safe at those dosage levels? I assume that cardiac side effects have been noted in the treatment of malaria but its use still continues. Seems that discontinuing its use here might be excessive caution.

15 posted on 04/02/2020 10:26:11 AM PDT by CommerceComet (Hillary: A unique blend of arrogance, incompetence, and corruption.)
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To: rintintin

Waste of government cash. Plenty of studies underway right now.

Duke . . .


16 posted on 04/02/2020 10:27:06 AM PDT by RinaseaofDs
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To: rintintin

“Up to $50 million has been approved”

About $10,000 for the drugs, and the rest for their effort.


17 posted on 04/02/2020 10:27:41 AM PDT by BeauBo
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To: nikos1121

I am calling bullsh*t on your anecdotal story. Let me guess what could cure it.... it’s Joe Biden being elected in November and DOnald Trump in jail for crimes against millenial’s feelings,... Then Covid-19 will run and hide.


18 posted on 04/02/2020 10:27:44 AM PDT by pburgh01 (Negan all the MSM)
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To: nikos1121
We’ve discontinued hydroxychloroquine + z-pak because of the cardiac issues it might cause, and most think it’s not helping anyway.

That's very disheartening. I can't believe America's only solution to this is to destroy the nation and lock everybody in their homes. I thought we were better than this.

Thank you for all of your efforts and for giving it your best.
19 posted on 04/02/2020 10:28:13 AM PDT by mmichaels1970
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To: Drango

How can they even put a figleaf on spending $50M on this?

All they need is a little reporting from the field. Good enough.


20 posted on 04/02/2020 10:28:25 AM PDT by 9YearLurker
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