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BREAKING: Tolicizumab (Actemra) shown to be more effective than hydroxychloroquine in treating coronavirus patients, Italian doctors say
Tech Startup ^ | March 27, 2020

Posted on 03/30/2020 10:53:40 PM PDT by aquila48

For the past two weeks now, we’ve been talking about hydroxychloroquine as the wonder drug in the fight against the deadly coronavirus. Two anti-malaria drugs hydroxychloroquine and chloroquine are shown to be effective in treating COVID-19 patients after controlled clinical study conducted by doctors ​in France shows that a combo of Hydroxychloroquine and Azithromycin (Z-Pak) cures 100% of coronavirus patients within 6 days of treatment.

However, according to doctors treating coronovirus patients in Italy, Tolicizumab, a drug used to treat moderate to severe rheumatoid arthritis, has been shown to be more effective than hydroxychloroquine. Tolicizumab is so effective that the FDA gives green lights to Phase III Tocilizumab Trial for COVID-19 pneumonia. In a related report, Italian doctors said that a 101-year-old Italian man who survived the 1918 Spanish flu pandemic and World War II, recovered from COVID-19.

In another report, scientists claim Tocilizumab has been shown to help cure 95 percent of critically ill coronavirus patients in China. Tocilizumab, which is marketed as Actemra, is taken by patients with rheumatoid arthritis to reduce inflammation. Chinese doctors gave it to 20 patients during the peak of of coronavirus epidemic. Nineteen of the patients were discharged within 14 days despite being critically ill. Actemra has now been approved for use in China and for trials in the US

In response to a question from another doctor on hydroxychloroquine, Dr. Giusppe Galati, an Italian doctor, said in a tweet: “Dear @DrLuizSilva1 despite the large noise on social media. Here in Flag of Italy they are trying several combinations of antiviral included the combination HCQ + azithro. Infectivologist refer little benefit. The unique drug which is causing impressive improvement is #Tolicizumab.”

Tocilizumab, also known as atlizumab, is an immunosuppressive drug, mainly for the treatment of rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. It is a humanized monoclonal antibody against the interleukin-6 receptor (IL-6R).


TOPICS: Business/Economy; Culture/Society; Extended News; News/Current Events
KEYWORDS: actemra; beelzebubbuzz; belongsinbloggers; bloggers; braking; chinavirusdrugs; garbage; hcqzpac; moneygrab; tolicizumab; trash
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This drug is similar to Hydroxychloroquine in that they both suppress the immune system during a cytokine storm. Perhaps one does a better job than the other.
1 posted on 03/30/2020 10:53:40 PM PDT by aquila48
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To: aquila48

How many doses do we have of this drug?

Where is this drug made?

What’s the cost per dose?


2 posted on 03/30/2020 10:55:38 PM PDT by Black Agnes
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To: Black Agnes

How many doses do we have of this drug?

Where is this drug made?

What’s the cost per dose?

Xxxxxxxxxxxxxxxxxxxxxxxxx

ADD: how did it work for Italians?


3 posted on 03/30/2020 11:00:22 PM PDT by thinden (How many Barr haters across America are being paid by Soros to attack Barr.)
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To: aquila48
Italian doctors said that a 101-year-old Italian man who survived the 1918 Spanish flu pandemic and World War II, recovered from COVID-19.

One tough uomo.

4 posted on 03/30/2020 11:01:10 PM PDT by Jeff Chandler (BLACK LIVES MAGA)
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To: aquila48

hmmm Hydroxychloroquine is 100% effective according to this article and Tolicizumab is 95% accordign to article, and Tolicizumab is more effective?

We have dozens and dozens of millions of doses of Hydroxychloroquine , and it’s savign lives- and is nearly 100% effective- Why do we have to wait for a clinical trial of Tolicizumab that could take months? IF Tolicizumab isn’t available because it hasn’t been approved yet, while the Hydroxy drug is available, and being used, how is Tolicizumab more effective? The drug being used is far more effective than a drug that isn’t available- except for clinical trials-

Will they forego the clinical trials? People are dying- They need drugs NOW-


5 posted on 03/30/2020 11:03:06 PM PDT by Bob434
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To: aquila48

Very good news!

But who comes up with these drug names?


6 posted on 03/30/2020 11:04:57 PM PDT by chris37 (Coronavirus wasn't born in a bowl of bat soup.)
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To: Jeff Chandler

We are now in the year 2020. Unless this 101 year old man “survived” the 1918 Spanish Flu in the womb, something is not right about this story.


7 posted on 03/30/2020 11:05:12 PM PDT by RegulatorCountry
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To: thinden

Just a quick check on GoodRx shows Tolicizumab ($1100) to Hydroxychloroquine ($20) is about 55x.


8 posted on 03/30/2020 11:06:15 PM PDT by JoSixChip (WuHoo flu is going to get you!)
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To: aquila48

Outlawed in Michigan in 1...... 2..... 3...... Done..... Thanks Gov!


9 posted on 03/30/2020 11:07:14 PM PDT by Lockbox
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To: chris37

“But who comes up with these drug names?”

I think they throw a dozen scrabble letters up in the air and find the most unpronounceable combination, and that’s the drug name. I’m taking several of those myself.


10 posted on 03/30/2020 11:11:12 PM PDT by aquila48 (Do not let them make you care!)
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To: aquila48

but plaquenil is easier to pronounce...


11 posted on 03/30/2020 11:11:56 PM PDT by cherry
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To: aquila48

I see a number of these bizarre names on various drug commercials, and I notice that several of the names end in “mab”, such as the one mentioned here. There has got to be some sort of drug naming convention that I’m unaware of.


12 posted on 03/30/2020 11:15:10 PM PDT by chris37 (Coronavirus wasn't born in a bowl of bat soup.)
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To: aquila48

I was curious who makes it - apparently Hoffman-La Roche.


13 posted on 03/30/2020 11:15:29 PM PDT by GnuThere
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To: JoSixChip

Hat tip josixchip:

“Just a quick check on GoodRx shows Tolicizumab ($1100) to Hydroxychloroquine ($20) is about 55x.”

Follow the money!


14 posted on 03/30/2020 11:15:37 PM PDT by thinden (How many Barr haters across America are being paid by Soros to attack Barr.)
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To: chris37

mab, monoclonal antibodies


15 posted on 03/30/2020 11:16:07 PM PDT by Black Agnes
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To: RegulatorCountry

“We are now in the year 2020. Unless this 101 year old man “survived” the 1918 Spanish Flu in the womb, something is not right about this story.”

I heard it from Brian Williams. He’s good with numbers.


16 posted on 03/30/2020 11:16:35 PM PDT by Mr. N. Wolfe
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To: aquila48
BREAKING: Tolicizumab (Actemra) shown to be more effective than hydroxychloroquine in treating coronavirus patients, Italian doctors say,

Or so the Germans would have us believe...

17 posted on 03/30/2020 11:19:25 PM PDT by higgmeister ( In the Shadow of The Big Chicken)
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To: Black Agnes

This isn’t a cheap drug. A ‘unit’ is around $125. Just a humble guess....five-day regiment of this (if it’s like the other drugs) would be over $600.

I should note, it’s been around for 10 years, and usually for severe forms of arthritis.


18 posted on 03/30/2020 11:22:38 PM PDT by pepsionice
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To: aquila48

Tolicizumab (Actemra) must be used to clean very large or very dirty fish tanks

Note to dem donors...don’t drink this cleaner, either.

On the other hand...


19 posted on 03/30/2020 11:25:27 PM PDT by Oscar in Batangas (January 20, 2017, High Noon. The end of an error.)
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To: chris37

Generally it’s a shorthand rendition of its chemical structure.

CC


20 posted on 03/30/2020 11:28:46 PM PDT by Celtic Conservative (My cats are more amusing than 200 channels worth of TV)
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