The 25,000 LY distant is the Canis Major Dwarf Galaxy, yes? That appears to be one that was swallowed up by the Milky Way. I grew up thinking the large Magellanic Cloud was the closest, but these dwarf galaxies seem to have usurped that distinction. I think there is a close one in Sagittarius as well (?).
My only point was the vastness of the universe and the in terms of space and time.