to enter the discussion with a new wrinkle, does taking the D3 with fat increase the ability to be absorbed and possibly reduce the dosage?
Got no clue. I usually take it along with my calcium caps to be sure the calcium is absorbed properly. I also take it at a different time than my prescription meds, as calcium can screw up the absorption of many prescription meds. I take prescription stuff with breakfast and supper, calcium and D at lunch, with another D near midnight when I get up to pee.