Hillary Clinton is no spring chicken, and Manson did just get married but...
Manson is 82 years old, 5'2" -120lbs, and has been living in a box for 45 years.
Clinton is 5'7", weight undisclosed, and reportedly a yoga fanatic in decent physical shape.
My guess is that Manson would be the bitch in that relationship.
Now THAT is an experiment I think would be worthy of a federal grant.