I like the .45, but prefer the 125 grain .357 magnum rd. Good ballistics and proven man stopper. The only downside is it is hell on K frame S&W revolvers.
I do have a Ruger SP-101 in .357. But after some testing with a chronograph I found that using .357 in a snub revolver doesn’t give the additional velocity. It does give a big ball of flame which tells me I’m just wasting powder.
So when I carry that piece I load it with .38 Spl in +P. Less recoil and less fireball. And it’s still a darned effective round. The Hornady Critical Defense load is pretty darned accurate considering the barrel length.
L
I carry one of two .357s, a Ruger SP101 3”-5 with Hornaday Custom 125gr JHP/XTP or a S&W 686 6”-6 with Hornaday Custom 158gr JHP/XTP. Both have oversized checkered wood combat grips.
The .357 magnum is the king of man-stoppers. The less than top notch stats listed are because the ammo is unable to reach its potential velocity in the shorter barrels tested.