The thing about Appalachia.... it’s not the only place in the world. If there’s no jobs around where you live....MOVE!!!
I remember seeing a guy at a washington state RV park in the late 1980’s that had just moved there from Detroit. He was working as a mechanic.
I asked him why he moved to Washington state and he said the automaker jobs were drying up in Detroit so he moved away.
Not all of them are stupid.
If you're healthy and have the right attitude, you can improve your situation. No sympathy for people who whine about their lot in life without doing anything about it.