There have been studies along these lines out there for a long time, decades at least.
My mother’s father’s side of the family had a problem with blood beginning to clot too easily in their early to mid 40s.
This happened to me several times in my early 40s. It was thought to possibly have been passed on from the survivors of the Black Plague.
If this is true, is it really as a result of an altered gene, or is it the result of the gene being present that somehow caused the survival of individuals who would naturally pass it on?
Leiden Factor V?