Yes indeed, there are many federal laws that cross state lines that are similar to federal drug laws. A few of the many examples would be fedgov control of education, the environment, health care, and national drug prohibition. They are all based on the same expansive view of the Commerce Clause.
You don’t want to address that, because these laws are widely accepted without objection.
Accepted by you apparently, but not by people who respect the Constitution.
You might be interested in the post I made above this one in the last few minutes.