I don’t think so......
Found this:
THE NEW MADRID FAULT SYSTEM EXTENDS 120 MILES SOUTHWARD from the area of Charleston, Missouri, and Cairo, Illinois, through New Madrid and Caruthersville, following Interstate 55 to Blytheville and on down to Marked Tree, Arkansas. It crosses five state lines and cuts across the Mississippi River in three places and the Ohio River in two places.
http://www.scchealth.org/docs/ems/docs/prepare/newmadrid.html