Sorry....you just seemed so set in your beliefs....I had to do a years worth of research....premarin and many hormones are given in PILLS.....they go thru the LIVER....which doesn’t make sense....that’s not where they are needed, and hormones do not NATURALLY go through our livers, other than the ones the LIVER needs. Also, with Premarin...a SURGE of hormone happens in the hour or two after the pill which is probably the cause of many of the problems that come with it. Bio-id creams compounded for the individual are put on the labia and do not go through the liver, but go directly (or as closely as possible) to the sexual organs needing those hormones....over a much slower time frame.
Balance of hormones is important too....you can’t just take some estrogen.....you need to test DHEA, Pregnenelone, Testosterone, Progesterone, and Estrogen.
Here’s an interesting article from my doctor, Dr. Jonathan Wright....http://www.tahoma-clinic.com/hotflashes.shtml
But, that article BARELY touches the research he’s done. Hope that helps. I, as you can tell, am passionate about this...having dealt with many ignorant doctors.
It’s not just the sexual organs that need these hormones, it’s the whole body. It certainly does make sense to bypass the liver, but in reality, injections are much more reliable and accurate than transdermal administration, and buttocks, hips, or abdomens are as good locations as any. But of course, many people are squeamish about giving themselves injections, and also the medical establishment and pharmaceutical companies that are trying to corner the market on hormone therapy would have a much easier time convincing the public and politicians that injectable treatments are scary and dangerous, than transdermal treatments.
Both pills and injections have the advantage of ensuring that the person the dose is intended for — and only that person — gets the whole dose. There was a scary case reported a couple of years back of a young boy who started showing some weird hormonal effects, which were eventually traced to his father’s transdermal testosterone treatments (NOT applied to his genitals) — apparently enough had been rubbing off on the boy in the course of ordinary father-son contact that the boy got the effects.