I think she is being set by the Bambster and Rahm for a coup. Obama wants to control all the branches of government which means having his people in power in both Houses. Nancy is expendable and is not an Obaminsta she will be replaced at the top.
I think you're absolutely right. This is all a set-up; she doesn't have to worry about the GOP or even about the CIA. She has to worry about the White House, and she should remember that Bambi is ruthless and plays for keeps.