Democrat on Democrat. More specifically, Ted “The Swimmer” Kennedy et al. vs. a legally blind black man.
Time to break out the popcorn, gents!
Now as far as how JFK would have aged: Medically speaking: the chronic STDs would have been cured. The Addison's Disease would have come under control, and the satyriasis would have perhaps, lessened with the aging of himself, and death and aging of those actresses with whom he was involved. He might have made it as far as 60.
Politically speaking, his impeachment would have come before the end of his first term. In foreign policy, his penchant for beginning military adventures for which he lacked the cojones to finish, and for which he definitely lacked the military and diplomatic skill to conduct, would have kept the Soviet Union alive and well.
IMHO, the shots from the Grassy Knoll will were fired by Old Joe Kennedy, so that his Hollywood Propaganda Mills could go go about creating the Camelot Legacy without the disastrous presence of JFK.
Packers versus Vikings for a Bears fan.
So you just enjoy the game and hope someone gets hurt. :-D