Sure you can! Try just plugging them in and see if they work. Since they are Microsoft, tho, chances are Bill wants you to have to download some drivers for them.
Don't be afraid to mess around with your Mac. They are very tolerant, even of 3-years olds (don't tell my kids I let their kids play on the blue and tangerine iMacs!)
I am learning I am less knowledgeable about computers than previously thought. I just don’t understand how viruses and such are so easily passed on a pc, yet not so much on a mac. Downloading things...why is this safer on a mac?