It is rude, crude, obnoxious, and gross. It "feels" like a liberal show, but it is an anti-PC Trojan Horse. It is LOADED with anti-liberal messages. Much more so than anti-conservative ones, though it does skewer the Social Right as well. I'll take it for the former, even if I have to endure the latter.
They basically skewer anyone from any side whenever there's a joke to be made! If you can't laugh at yourself, and at the extremes of your own side, then you shouldn't laugh at anyone else!
I read an interview with Trey and Matt in which Matt(I think) said "We don't like Republicans but we REALLY don't like Democrats."