I have terrible depth perception, as does a friend of mine. When I first found out, I was a bit shocked that I am able to drive so well. Doctor told me that when you grow up with it, your brain learns to process other visual clues to make up fo rit. However, I am terrible in sports.
Yes, if it's a life-long condition, you probably adapt (since you've never known it any other way, after all). I think it's probably different if your brain has gotten used to handing on signals one way all your life, and then the eyes start passing it the wrong information.