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Israeli doctor heads Merck team that has developed vaccine against cervical cancer
ISRAEL21c ^ | June 14, 2006 | Staff

Posted on 06/23/2006 7:21:19 AM PDT by veronica

An Israeli-born doctor stands at the head of team from pharmaceutical giant Merck & Co. Inc. who announced this week the FDA approval of the first vaccine to prevent cervical cancer

Senior director of Clinical Research, Merck Research Laboratories Dr. Eliav Barr, originally from Haifa, said about bout the genetically engineered vaccine Gardasil, "This is the first time we have been able to state that administration of the vaccine is going to have an effect on cervical cancer."

In the United States, almost 10,000 women develop cervical cancer each year, leading to 3,000 deaths. In the developing world, the problem is far worse, probably because women are less likely to get screenings that can catch unusual growths before they become cancerous. Worldwide, cervical cancer kills 300,000 women a year.

Almost all the cases of cervical cancer are caused by infection with the human papilloma virus, or HPV, which causes normal cells to multiply out of control. Some strains of HPV lead to cancer (two strains account for 70% of cervical cancers), and others cause genital warts.

Because cervical cancer does not occur in women who have not contracted HPV, Merck, under Barr's guidance, has developed what is essentially the world's first cancer vaccine.

Public health experts called the Gardasil vaccine a major advance against the disease. "This vaccine is a significant advance in the protection of women's health in that it strikes at the infections that are the root cause of many cervical cancers," acting Food and Drug Administration Commissioner Andrew von Eschenbach told Reuters.

Given in three doses over six months, Gardasil targets four HPV types believed to cause more than 70 percent of cervical cancer cases and 90 percent of genital warts. The vaccine was approved for use in girls and women ages 9 to 26, Merck said.

Barr started his medical career as a cardiologist. So it was quite a shift in the mid-1990s when his employer, Merck, asked Barr to join a team that was developing an HPV vaccine.

"I had to go look up what HPV meant," Barr, 42, told The Intelligencer. "This is about as far as you can get from medicine."

Barr said he's overwhelmed by the feeling that he's helped develop something that will save millions of lives.

"It's very difficult to describe," Barr said. "One gets very emotional. It's really a once-in-a-lifetime kind of thing."

The biggest challenge for Gardasil comes because of the target market: adolescent girls. HPV is a sexually transmitted disease, and some 20 million American men and women have it. To prevent women from getting cervical cancer, women must be inoculated before they become sexually active. But for some parents and religious groups, that might be a touchy question.

Merck's Barr says that won't be a problem. "You have to understand what's at stake here," he told Forbes. "Regardless of your background, as a parent, you want to be able to protect your child against cancer."


TOPICS: Culture/Society; Extended News; Foreign Affairs; Israel; News/Current Events
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To: pbrown
For those who practice abstinence, they don't have to worry about that being the cause of Cervical cancer.

Sorry just funnin'ya and I just learned how to post pics and wanted to post this one.

101 posted on 06/23/2006 9:07:19 AM PDT by Dosa26
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To: ThisLittleLightofMine
Do you really believe that all children have sex before marriage?

Not all but quite a few. I would even say the vast majority... EspeciAlly today when age at marriage is so high... And denying it is having one's eyes wide shut...
102 posted on 06/23/2006 9:08:40 AM PDT by Alama
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To: Dosa26
Sorry just funnin'ya and I just learned how to post pics and

It is fun posting pictures. I haven't posted one in so long I can't remember the last one I did. Maybe I'll blow the dust off my photobucket and start again. lol

103 posted on 06/23/2006 9:10:58 AM PDT by processing please hold (If you can't stand behind our military, stand in front of them.)
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To: ThisLittleLightofMine
I don't dare respond to someone other than a Christian with this ... it would totally rock their world ... but when out in a restaurant she'll actually require a prayer before we eat. Sometimes, I'm hungry and forget and then I hear a AHEM ... she quietly thanks Him.

She's a straight A student, honors, pretty, popular and most importantly a genuine Christine. Her friends are the same way. Yes, genuine Christian households are different.

We also don't fall for the liberal scare tactics and undermining that they constantly brain wash people with. We also don't have to worry about their stances corrupting our kids -

give em birth control - "you know they're going to do it anyway"
give guys condoms - "just in case"
give them explicit sex information so they know what they're doing - you "just know they're going to indulge"

and on and on it goes.

What gets little press time is a growing movement with kids to remain pure. They see through this nonsense. They don't want to wind up like these people with regrets that constantly push precisely what is wrong while trying to "protect them". Reminds me of the hideous PRO abortion stance - "it's for the kids" - mutilate the inconvenient baby to death.
104 posted on 06/23/2006 9:14:13 AM PDT by nmh (Intelligent people recognize Intelligent Design (God) !)
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To: Alama

I suppose we should buy alcohol for them too, in addition to purchasing condoms and providing other means of birth control. We also shouldn't have a problem with drugs...as all the kids are doing it. This mentality is SO MISGUIDED.


105 posted on 06/23/2006 9:14:41 AM PDT by ThisLittleLightofMine
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To: ThisLittleLightofMine
<<< I just stated that once again one of the natural consequences of premarital sex are being removed. >>>

why is that a bad thing?

if you say actions should have consequences, then should we withhold all corrective measures for consequences of actions we don't approve? No cholesterol reduction pill for people who ate too much fatty food, no cold medicine for kids who played too long in the rain, no help for the idiot who jaywalked and got ran over by a bus, no vaccine for AIDS because we're sure they all deserve the disease, no dental fillings for the guy who didn't brush and floss properly, ...

106 posted on 06/23/2006 9:18:06 AM PDT by Republican Party Reptile
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To: ThisLittleLightofMine

Well about alcohol: I believe that the scare tactics used against alcohol drinking are backfiring. Today we forbid them to drink until they are 21, then they go into binge drinking...

If you introduce them to drinking in a family environment, then they learn drinking responsibly...





107 posted on 06/23/2006 9:18:40 AM PDT by Alama
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To: ThisLittleLightofMine

"You don't just catch this cancer, it comes from having promiscuous sex outside of marriage.
"

Yes, yes....or it comes from having sex with just one partner who somehow managed to become infected with the virus at some point.

Or it comes from being sexually assaulted by someone who has this virus.

You are aware (well, maybe you are not) that HPV is pretty much symptomless in men? That means that your sweet virginal daughter's bridegroom, who may not be as virginal as she is, could be carrying HPV as they walk down the aisle.

Get informed. It could save your daughter's life.


108 posted on 06/23/2006 9:27:04 AM PDT by MineralMan (non-evangelical atheist)
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To: MineralMan
Get informed. It could save your daughter's life.

I don't think they want that... If she gets cancer, they'll tell she deserved it...
109 posted on 06/23/2006 9:30:16 AM PDT by Alama
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To: nmh

Transmission of HPV through routes other than sexual is definitely possible. One may be exposed to HPV simply by shaking hands as suggested in the finding of HPV virus under fingernails.
Sexually Transmitted Infections 1999 Oct;75(5):317-9:

Detection of human papillomavirus DNA on the fingers of patients with genital warts.

Sonnex C, Strauss S, Gray JJ, Department of GU Medicine, Addenbrooke's Hospital, Cambridge, England.

“14 men and eight women with genital warts had cytobrush samples taken from genital lesions, finger tips, and tips of finger nails. Samples were examined for the presence of HPV DNA by the polymerase chain reaction.

HPV DNA was detected in all female genital samples and in 13/14 male genital samples. HPV DNA was detected in the finger brush samples of three women and nine men. The same HPV type was identified in genital and hand samples in one woman and five men.

This study has identified hand carriage of genital HPV types in patients with genital warts. Although sexual intercourse is considered the usual mode of transmitting genital HPV infection, our findings raise the possibility of transmission by finger-genital contact.”


110 posted on 06/23/2006 9:33:55 AM PDT by SC DOC
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To: nmh

"Perhaps you need to be more selective in what KIND of a school it is. Ours go to a wonderful Christian school. "




That's good, but not any assurance. My first time having sex was at a Church camp, with the daughter of a pastor. And she wasn't a slut, either. We just sort of fell into it, so to speak.

We both felt terrible the next day and did a lot of praying for forgiveness, but there it is.

You are terribly mistaken if you believe that proper training will prevent situations like that from happening. Sometimes, teenagers have sex, despite themselves.


111 posted on 06/23/2006 9:36:26 AM PDT by MineralMan (non-evangelical atheist)
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To: ThisLittleLightofMine
Well hopefully if my daughter decide to marry men who have had previous relations, they would be tested for HPV along with AIDS etc.

There currently is no test for HPV in men. Guess she'll just have to keep her fingers crossed!
112 posted on 06/23/2006 9:38:38 AM PDT by Nathan Jr.
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To: Alama

what the heck difference does it make if he's Isreali or not?

who cares?!


113 posted on 06/23/2006 9:38:56 AM PDT by Hammerhead
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To: Nathan Jr.

"Guess she'll just have to keep her fingers crossed!"

Or her legs. (I simply could not resist).


114 posted on 06/23/2006 9:42:23 AM PDT by MineralMan (non-evangelical atheist)
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To: nmh

They like to toss insults at people for no reason.
Best to ignore the troll.


115 posted on 06/23/2006 9:42:26 AM PDT by Darksheare (This is a test of the emergency tagline system. Had there been an emergency, you would have heard...)
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To: Alama

"I don't think they want that... If she gets cancer, they'll tell she deserved it..."



Sorry, but I can't be that judgmental. I think such folks mean well, but they're uninformed. I'm sure they don't wish cancer on the unchaste. But, they mistakenly believe that if their daughter is a virgin upon marriage she cannot get this virus.

What they don't understand is that men can have it with no symptoms, and that there is no test for it if there are no lesions.

It's just ignorance of the facts, plus a mistaken belief that teenagers who are "brought up right" won't slip and give into their natural sexual urges.


116 posted on 06/23/2006 9:46:01 AM PDT by MineralMan (non-evangelical atheist)
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To: SC DOC

So are you sugesting we shouldn't shake hands with anyone?

What are the stats on this form or transmission?

BTW, the thread is about cervical cancer


117 posted on 06/23/2006 9:52:27 AM PDT by nmh (Intelligent people recognize Intelligent Design (God) !)
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To: nmh

No, it is about a vaccine against HPV which is the cause of cervical cancer....


118 posted on 06/23/2006 9:53:15 AM PDT by Alama
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To: nmh

No, it is about a vaccine against HPV which is the cause of cervical cancer....


119 posted on 06/23/2006 9:53:18 AM PDT by Alama
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To: MineralMan
Oh, MineralMan just what are we going to do with you?

"You are terribly mistaken if you believe that proper training will prevent situations like that from happening. Sometimes, teenagers have sex, despite themselves."

I add you might see something in a store that you'd like to have but can't afford. The "urge" might be to steal it - especially if there are no video cameras and no one is looking. What's different for some is that they know stealing is wrong and don't steal. Shocking as this may be some understand and accept that sex before marriage is wrong too. Stealing is wrong if your excuse is you can't afford it and might even get away with it. Those with proper values and beliefs don't have this issue you keep pushing - "they're going to have sex anyway".
120 posted on 06/23/2006 9:57:06 AM PDT by nmh (Intelligent people recognize Intelligent Design (God) !)
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