NautiNurse will grab something and ask you to cough twice....
NeverGore :^)
If running Internet Explorer, poke tools, internet options, and under the general tab, delete files under temporary internet files.
In Firefox, poke tools, options, privacy, and clear the cache.
For general cleanup, ccleaner and beclean ( google them ) are very useful, but check carefully through all their options before running, so you don't delete something you may need.