If the meaning of this vote is that the member states want to retain more independence, then there will be less financial and political integration. In this case problems like we are seeing in Italy today will multiply, and the EUro will have some real trouble. They may have to split it up. Maybe the old EC "core group" will keep it as a sort of "supranational DM," but I think that a currency that is not issued by a true nation cannot last for long. The same will be true about the ECB.
The EU could become much like the OCED. We may have just witness the high water mark for European integration in this generation, perhaps in our lifetimes.
Hmmm - probably smart to sell oil tomorrow - as those who were betting that the euro would gradually displace the dollar come to realize just what you are predicting about he euro. Bet on relatively long term pressure depressing oil prices.