Uncle Sugar taught me a tactic in the service called defense in depth.......multiple antivirus and malware programs such as spybot w/ spy blaster, webroot spysweeper, ad-aware, zone alarm pro and AVG works well......
Sort of like a locked gate at the driveway, an alarm on the doors, 4 rottweillers and a 12 gauge shotgun in theory......
Back when I did computer maintenance, we did a lot of work on Tempest machines for Uncle Sugar's contractors.