Two other things to consider:
1. Have you tried ad-aware? It is free, too, and it catches some things that spybot does not. (And spybot catches some things that ad-aware does not, so it is good to have both).
2. Are you deleting them, only to find that they immediately return again? If so, what OS are you using?
I tried adaware once upon a time, and it seemed to ATTRACT spyware like a magnet! LOL Perhaps using it in conjunction with spybot might make a difference.
No, so far nothing I have removed has returned. I just have four stubborn items that I cannot get spybot to remove.