My prayers are even more so with the entire family. We went through this with my mother in law.
Please make sure her children are keeping track of the meds she is beiing given. Over medication pushed my MIL over the edge and then the instant stop of them led to her death.
The only other thing I can say is, be there for your wife. Its going to be rough.
A few months ago, she was having a lot of problems and my wife's youngest brother dropped over for coffee one Sunday morning. She finished her breakfast and took her pills from the dispenser my wife had bought and was loaded each week by this son's wife (both women are RN's). Ten minutes later she came back to take her meds agains and argued with her son that she hadn't taken the meds. When you are in your mid 80's ODing on your meds is not good. Later the bottom dropped out and they found a place for her to stay.
Sometimes when my wife calls, from a one way listener side, the calls sound fairly normal. Then on other days, my wife has to repeat everything 10 to 12 times (there is no hearing problem)
Her family is behind her and the in laws like me are backing the immediate family for as long as it takes!