Ad-aware (make sure it is Lavasoft, there are bad imposters)
http://www.lavasoftusa.com/
and Spybot Search and Destroy, PepiMK Software,
http://www.safer-networking.org/en/index.html
work well and are free downloads. Spybot can dig out several of the Cool Web Search variants, which are really tenacious. Download as files to the disk, shut down your computer normally and then restart in safe mode, and install and run them.
Install and set up in the start menu folder Spywareblaster. This will run continuously in the background and block spyware in operation. Works well.
http://www.javacoolsoftware.com/products.html
These all update manually in the free versions. Update once a week or so.
I also browse with Firefox with the Java turned off. Firefox does not accept ActiveX scripts. Obviously many web sites won't work properly under these conditions, but why leave the front and the rear doors open all the time, but instead unlock them after consideration?
Javacool also has a Beta SpywareGuard, which I will report on after I have run it for a while. Supposed to do very good stuff.
Good luck on your infestation. I think Spybot will get it out.
Ad-aware, Spybot Search and Destroy
Been there done that...no joy.
I hate to do it but I think I'm going to take into a pro in the morning.
AAAGGGGGHHHHHH!!!