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Your sense of the word "wisdom" is not that of the original text. Here is the American Heritage definition:

wisdom (wîz´dem) noun
1. Understanding of what is true, right, or lasting; insight: "One cannot have wisdom without living life" (Dorothy McCall).
2. Common sense; good judgment: "It is a characteristic of wisdom not to do desperate things" (Henry David Thoreau).
3. a. The sum of scholarly learning through the ages; knowledge: "In those homely sayings was couched the collective wisdom of generations" (Maya Angelou). b. Wise teachings of the ancient sages.
4. A wise outlook, plan, or course of action.
5. Wisdom. Bible. Wisdom of Solomon.
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The Greek word (translated "wisdom") is: sofia:
sofia - wisdom, insight, intelligence
sofo - wise, experienced
In the context of the original quotation, it particularly means the wisdom of the learned and politically dominant classes.

The Greek word translated "understanding" is sunesi.
sunesi - understanding, insight
suneto - intelligent, possessing understanding

The amplified version may help your understanding of the Greek word that is translated "wisdom." The word used in I Cor 1:19 has the more traditional sense of the word, meaning "intelligence" or "cleverness."

For it is written, I will baffle and render useless and destroy the learning of the learned and the philosophy of the philosophers and the cleverness of the clever and the discernment of the discerning; I will frustrate and nullify [them] and bring [them] to nothing.

I sincerely hope this help you to understand what I intended in my earlier post.

Thanks,
Russ

For it is written, I will baffle and render useless and destroy the learning of the learned and the philosophy of the philosophers and the cleverness of the clever and the discernment of the discerning; I will frustrate and nullify [them] and bring [them] to nothing.

So dear friend, why does the Creationist side of the debate rely upon half-truths, selective facts, or down right lied to support thier side?

I'll accept that God's Wisdom trumps man's Wisdom. I don't understand the point of the quote about the destruction of man's "wisdom" or the definition of "wisdom" for the purpose of the quote.

Further, I don't know what point you are making with respect to science vs. creationism. Is the quote that "I will destroy the wisdom of the wise, and will bring to nothing the understanding of the prudent" intended to bolster an argument that the research and learning and wisdom of scientists is wrong and that the research and learning and wisdom of theologians is correct? I'm just lost. What is the intent of the quotation?